ALLOPREGNAN-3ALPHA-OL-20-ONE–CAS 516-54-1
FUCTION
It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the
case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear
infection, it is often applied in liquid form, as ear drops. Fungal infections can be slow to clear up, so the usual course for an
anti-fungal agent is, in general, longer than the typical 3-7 days of an antibiotic. Clotrimazole is also commonly found in
conjunction with Betamethasone, known as Lotriderm, to add steroid properties. Additionally, Clotrimazole is used to treat the
sickling of cells (related to sickle cell anemia) by blocking ion channels in the RBC (red blood cell) membrane, keeping ions and
water within the cell.
Clotrimazole manufacturers antifungal drugs, the white candida can inhibit the transition from spore for invasive hyphae.
Clotrimazole has broad-spectrum antifungal live sex, the skin tinea, tinea capitis MAO bacteria, fungi, cryptococcus music
bacterium, shaded and candida has good antibacterial activity
| Items | Standard | Results |
| APPEARANCE | Off white to white powder | White powder |
| IDENTIFICATION | A: IR B: Retention time |
Complies Complies |
| WATER | ≤0.5% | 0.06% |
| HEAVY METALS | ≤0.002% | Complies |
| ISOMERS | SFBD1≤0.15% | Undetected |
| SFBD2≤0.15% | Undetected | |
| SFBE≤0.15% | Undetected | |
| RELATED SUBSTANCES | SFBA-1≤0.15% | 0.04% |
| SFBMA≤0.15% | Undetected | |
| CHLORO-SFB≤0.15% | 0.05% | |
| DiSFBMA-SFB≤0.15% | 0.02% | |
| Methyl-SFB≤0.15% | Undetected | |
| Pentafluoro-phenol≤0.15% | Undetected | |
| Amino-SFB≤0.15% | Undetected | |
| Any unknown impurity≤0.1% | 0.04% | |
| Total impurity≤1.0% | 0.21% | |
| RESIDUE SOLBENTS | Methanol≤3000ppm | Undetected |
| Isopropyl alcohol≤5000ppm | 19ppm | |
| Dichloromethane≤600ppm | Undetected | |
| Tetrahydrofuran≤720ppm | Undetected | |
| Acetic acid≤5000ppm | Undetected | |
| Toluene≤890ppm | Undetected | |
| Chlorobenzene≤360ppm | Undetected | |
| Methyl tert-butyl ether≤5000ppm | 103ppm | |
| ASSAY | ≥99.0% | 99.8% |
| RESULT: It complies to prescribed enterprise standard | ||
