Factory Price For Tropinone - 4-Amino-3,5-Dichloroacetophenone CAS37148-48-4 – Kaimubuke
Factory Price For Tropinone - 4-Amino-3,5-Dichloroacetophenone CAS37148-48-4 – Kaimubuke Detail:
3, 5-dichloro-4-aminoacetophenone, which is a beige crystal. Melting point of 158-160 ℃. Insoluble in cold water, slightly soluble in hot water, soluble in ethanol, ether, benzene and other organic solvents.
Production method: chlorination of aminoacetophenone. Add p-aminoacetophenone and acetic acid (80%) into the reaction pot, stir to dissolve, quickly add chlorine-containing glacial acetic acid solution, feed temperature 5℃, add, immediately put into ice water precipitation, filtration, water washing, the obtained crude product with ethanol recrystallization, the finished product.
Application: The product is an intermediate in the synthesis of antitussive and antiasthmatic drug clasthenin.
CAS | 37148-48-4 | Name | 4-Amino-3,5-dichloroacetophenone |
Appearance | yellow powder | MF | C8H7Cl2NO |
Purity | 99%min | EINECS No | 253-368-1 |
Application | Pharmaceutical /industrial/animal and so on | Grade | EP,USP,CP,JP |
Boiling point | 351.5±42.0 °C at 760 mmHg
|
Melting point | 162-166 |
density | 1.4±0.1 g/cm3
|
Molecular Weight | 371 |
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